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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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Famous people who died from poisoning or drug overdose include, Adolf Hitler, Socrates, Juan Ponce de Leon, Marilyn Monroe, Judy Garland, and John Belushi.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.