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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Cancer has been around as long as humankind, but only in the second half of the twentieth century did the number of cancer cases explode.
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Nearly all drugs pass into human breast milk. How often a drug is taken influences the amount of drug that will pass into the milk. Medications taken 30 to 60 minutes before breastfeeding are likely to be at peak blood levels when the baby is nursing.
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Alcohol acts as a diuretic. Eight ounces of water is needed to metabolize just 1 ounce of alcohol.