Why would the flu not be a good malady for studying in a N of 1 ...

[abern]

Why would the flu not be a good malady for studying in a N of 1 Randomized Clinical Trial methodology? Why would a group design be better?
 
  What will be an ideal response?

Question 2

What is the difference between a qualitative and a quantitative independent variable?
 
  What will be an ideal response?

[frejo]

Answer to Question 1

The flu doesn't meet an important criterion associated with successful use of the N of 1 RCT. The flue is neither stable nor chronic; it can't be evaluated over time because it doesn't last long enough. A group design would be better because a researcher can evaluate different treatments over the relatively short course of the flu, without worrying that the symptoms would disappear before different treatments could be evaluated.

Answer to Question 2

A qualitative independent variable is one for which the various levels or conditions differ by category; the differences across group isn't one of more or less. On the other hand, a quantitative independent variable differs along a continuum, so you can say that one condition involves more or less of something.