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When blood is exposed to air, it clots. Heparin allows the blood to come in direct contact with air without clotting.
Before a vaccine is licensed in the USA, the Food and Drug Administration (FDA) reviews it for safety and effectiveness. The CDC then reviews all studies again, as well as the American Academy of Pediatrics and the American Academy of Family Physicians. Every lot of vaccine is tested before administration to the public, and the FDA regularly inspects vaccine manufacturers' facilities.
Human kidneys will clean about 1 million gallons of blood in an average lifetime.
People with alcoholism are at a much greater risk of malnutrition than are other people and usually exhibit low levels of most vitamins (especially folic acid). This is because alcohol often takes the place of 50% of their daily intake of calories, with little nutritional value contained in it.
In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.