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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
A strange skin disease referred to as Morgellons has occurred in the southern United States and in California. Symptoms include slowly healing sores, joint pain, persistent fatigue, and a sensation of things crawling through the skin. Another symptom is strange-looking, threadlike extrusions coming out of the skin.
In 1864, the first barbiturate (barbituric acid) was synthesized.
Essential fatty acids have been shown to be effective against ulcers, asthma, dental cavities, and skin disorders such as acne.
Throughout history, plants containing cardiac steroids have been used as heart drugs and as poisons (e.g., in arrows used in combat), emetics, and diuretics.