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Although the Roman numeral for the number 4 has always been taught to have been "IV," according to historians, the ancient Romans probably used "IIII" most of the time. This is partially backed up by the fact that early grandfather clocks displayed IIII for the number 4 instead of IV. Early clockmakers apparently thought that the IIII balanced out the VIII (used for the number 8) on the clock face and that it just looked better.
There are approximately 3 million unintended pregnancies in the United States each year.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
Aspirin is the most widely used drug in the world. It has even been recognized as such by the Guinness Book of World Records.
Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.