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Side effects from substance abuse include nausea, dehydration, reduced productivitiy, and dependence. Though these effects usually worsen over time, the constant need for the substance often overcomes rational thinking.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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The average adult has about 21 square feet of skin.
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During the twentieth century, a variant of the metric system was used in Russia and France in which the base unit of mass was the tonne. Instead of kilograms, this system used millitonnes (mt).
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.