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The first war in which wide-scale use of anesthetics occurred was the Civil War, and 80% of all wounds were in the extremities.
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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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In 1844, Charles Goodyear obtained the first patent for a rubber condom.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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There are 60,000 miles of blood vessels in every adult human.