Which of the following medications has been demonstrated to ...

[Wadzanai]

Which of the following medications has been demonstrated to improve lung procurement after a patient has been declared brain dead?
 
  A. pulmonary surfactant
  B. third generation cephalosporin
  C. dexmedetomidine
  D. Solu-Medrol

Question 2

Which of the following factors are standard criteria for lung donation? I. smoking history of less than 50 pack-years II. donor age less that 70 years III. Pao2/Fio2 greater than 300 with an Fio2 of 1.0 IV. absence of chest trauma
 
  A. I, II only
  B. III, IV only
  C. I, III, IV only
  D. II, III, IV only

[phuda]

Answer to Question 1

ANS: D
A. Incorrect response: See explanation D.
B. Incorrect response: See explanation D.
C. Incorrect response: See explanation D.
D. Correct response: Aggressive management of brain dead patients to optimize lung procurement typically includes monitoring central venous pressure, diuresis, corticosteroids, and judicious use of fluids to maintain adequate arterial pressure, with vasopressor use as needed. An intravenous bolus of Solu-Medrol (15 ml/kg) once a patient has been declared brain dead has demonstrated to improve oxygenation and lung procurement, mainly likely by mediating the pro-inflammatory response that follows brain death

Answer to Question 2

ANS: B
A. Incorrect response: See explanation B.
B. Correct response: Standard criteria for lung donation are:
  Pao2/Fio2 greater than 300 while breathing and Fio2 of 1.0
  5 cm H2O PEEP
  Clear chest radiograph
  Age less than 55 years
  No chest trauma
  Absent aspiration, sepsis, or purulent secretions
  Smoking history less than 20 pack-years
  Absent history of malignancy
C. Incorrect response: See explanation B.
D. Incorrect response: See explanation B.

[Wadzanai]

TY

[phuda]

Happy to Help