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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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On average, the stomach produces 2 L of hydrochloric acid per day.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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In inpatient settings, adverse drug events account for an estimated one in three of all hospital adverse events. They affect approximately 2 million hospital stays every year, and prolong hospital stays by between one and five days.
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The longest a person has survived after a heart transplant is 24 years.