In which of the following conditions will erythrocyte ...

[jjjetplane]

In which of the following conditions will erythrocyte concentration of 2,3-DPG be decreased?
 
  a. Anemia
  b. Banked blood
  c. High pH
  d. Hypoxemia

Question 2

According to the Bohr effect, when the pH drops, what happens? 1. The affinity of Hb for O2 decreases. 2. The Hb saturation for a given PO2 falls. 3. The Hb saturation for a given PO2 rises.
 
  a. 1 and 2 only
  b. 2 only
  c. 2 and 3 only
  d. 1, 2, and 3

[ecabral0]

Answer to Question 1

ANS: B
Erythrocyte concentrations of 2,3-DPG in banked blood decrease over time. After a week of storage, the 2,3-DPG level may be less than one-third of the normal value.

Answer to Question 2

ANS: A
The impact of changes in blood pH on hemoglobin affinity for O2 is called the Bohr effect. As shown in Figure 12-10, the Bohr effect alters the position of the HbO2 dissociation curve. A low pH (acidity) shifts the curve to the right, decreasing Hb affinity for O2 and thus O2 saturation.

[jjjetplane]

Excellent

[adf223]

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