Author Question: Standard bicarbonate is calculated by use of which of the following? a. Hender-son-Hasselbalch ... (Read 12 times)

james · **on:** Jul 16, 2018

Standard bicarbonate is calculated by use of which of the following?

a. Hender-son-Hasselbalch equation c. Lambert-Beer law equation
b. Two-point calibra-tion method d. Levy-Jennings chart

Question 2

Which of the following would create the lowest P50?

a. pH = 7.26 c. PCO2 = 32 mm Hg
b. pH = 7.35 d. Temperature = 39C

yotaSR5 · **Reply #1 on:** Jul 16, 2018

Answer to Question 1

ANS: A
HCO3 is derived from measurements of pH and PaO2 by using the Henderson-Hasselbalch equa-tion. A two-point calibration is a quality assurance test that is performed at least three times daily for the measuring electrodes. The Lambert-Beer law is applied in oximetry to determine the con-centration of hemoglobin. A Levy-Jennings chart is used to record quality control data for a blood gas machine.

Answer to Question 2

ANS: C
A pH of 7.26 and 7.35 are acidotic and will cause a right shift in the oxyhemoglobin dissociation curve, increasing the P50 above 27 mm Hg (normal). A PCO2 of 32 mm Hg indicates alkalosis and will shift the oxyhemoglobin dissociation curve to the left, lowering the P50 below 27 mm Hg. A temperature of 39 C is hyperthermia and will cause a right shift in the curve, increasing the P50 above 27 mm Hg.