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Multiple experimental evidences have confirmed that at the molecular level, cancer is caused by lesions in cellular DNA.
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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
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In the United States, congenital cytomegalovirus causes one child to become disabled almost every hour. CMV is the leading preventable viral cause of development disability in newborns. These disabilities include hearing or vision loss, and cerebral palsy.
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Illicit drug use costs the United States approximately $181 billion every year.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.

