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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
About 80% of major fungal systemic infections are due to Candida albicans. Another form, Candida peritonitis, occurs most often in postoperative patients. A rare disease, Candida meningitis, may follow leukemia, kidney transplant, other immunosuppressed factors, or when suffering from Candida septicemia.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.
Between 1999 and 2012, American adults with high total cholesterol decreased from 18.3% to 12.9%
There are more nerve cells in one human brain than there are stars in the Milky Way.