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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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In 1864, the first barbiturate (barbituric acid) was synthesized.
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Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
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This year, an estimated 1.4 million Americans will have a new or recurrent heart attack.
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The first monoclonal antibodies were made exclusively from mouse cells. Some are now fully human, which means they are likely to be safer and may be more effective than older monoclonal antibodies.