A person takes sertraline (Zoloft) 100 mg PO daily for ...

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A person takes sertraline (Zoloft) 100 mg PO daily for posttraumatic stress disorder. Which change in sleep is likely secondary to this medication? The patient will have:
 
  a. more dreams.
  b. less REM sleep.
  c. excessive sleepiness.
  d. less slow-wave sleep.

Question 2

A person takes lorazepam (Ativan) 2 mg PO BID PRN for anxiety. When the person takes this medication, which change in sleep is anticipated? The patient will:
 
  a. have fewer dreams.
  b. enter sleep through REM.
  c. have less slow-wave sleep.
  d. have more complaints of pain.

[bpool94]

Answer to Question 1

B
Sertraline (Zoloft) is an SSRI anti-depressant medication, which suppresses REM sleep. Dreams would decrease because they occur during REM. Benzodiazepines reduce slow-wave sleep. SSRIs have a side effect of insomnia.

Answer to Question 2

C
Lorazepam is a benzodiazepine, which reduces slow-wave sleep. REM sleep would likely increase. Persons with narcolepsy often enter sleep through REM.

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Thanks for the timely response, appreciate it

[debra928]

TYSM