A nurse explains galantamine (Razadyne) therapy to family members ...

[newbem]

A nurse explains galantamine (Razadyne) therapy to family members of a patient who is to begin treatment with the drug. What information should be included? Select all that apply.
 
  a. Facial flushing and leg cramps might worsen.
  b. It acts by making more dopamine available.
  c. Report slow heartbeat immediately.
  d. Restrict fluid intake to 1500 ml/day.
  e. Side effects include GI symptoms.

Question 2

A nursing assistant reports to the nurse that a patient diagnosed with AD is experiencing severe diarrhe
 
  a. Administration of which classification of medication is most associated with this problem?
  a. ChE inhibitor
  b. Secretase inhibitor
  c. NDMA antagonist
  d. Nonsteroidal antiinflammatory drug

[alexanderhamilton]

Answer to Question 1

A, C, E
Anticipated side effects include nausea and vomiting, diarrhea, facial flushing, sweating, rhinitis, bradycardia, and leg cramps. The incorrect options include fluid restriction and stimulation of dopamine. Adequate intake is necessary to address GI symptoms. Galantamine stimulates action of ACh, not dopamine.

Answer to Question 2

A
ChE inhibitors used in treatment of AD increase the availability of ACh, which stimulates action of the parasympathetic nervous system. This stimulation is likely to produce diarrhea. The other classifications work by different actions.

[newbem]

Thanks for the timely response, appreciate it

[ultraflyy23]

TYSM