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Human kidneys will clean about 1 million gallons of blood in an average lifetime.
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In most cases, kidneys can recover from almost complete loss of function, such as in acute kidney (renal) failure.
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Hyperthyroidism leads to an increased rate of metabolism and affects about 1% of women but only 0.1% of men. For most people, this increased metabolic rate causes the thyroid gland to become enlarged (known as a goiter).
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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Blood in the urine can be a sign of a kidney stone, glomerulonephritis, or other kidney problems.