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Medication errors are more common among seriously ill patients than with those with minor conditions.
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By definition, when a medication is administered intravenously, its bioavailability is 100%.
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Disorders that may affect pharmacodynamics include genetic mutations, malnutrition, thyrotoxicosis, myasthenia gravis, Parkinson's disease, and certain forms of insulin-resistant diabetes mellitus.
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In 2010, opiate painkllers, such as morphine, OxyContin®, and Vicodin®, were tied to almost 60% of drug overdose deaths.
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According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.