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The heart is located in the center of the chest, with part of it tipped slightly so that it taps against the left side of the chest.
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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
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Oliver Wendell Holmes is credited with introducing the words "anesthesia" and "anesthetic" into the English language in 1846.