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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
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Drug-induced pharmacodynamic effects manifested in older adults include drug-induced renal toxicity, which can be a major factor when these adults are experiencing other kidney problems.
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Medication errors are three times higher among children and infants than with adults.
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In the United States, an estimated 50 million unnecessary antibiotics are prescribed for viral respiratory infections.
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Eat fiber! A diet high in fiber can help lower cholesterol levels by as much as 10%.