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Ether was used widely for surgeries but became less popular because of its flammability and its tendency to cause vomiting. In England, it was quickly replaced by chloroform, but this agent caused many deaths and lost popularity.
Intradermal injections are somewhat difficult to correctly administer because the skin layers are so thin that it is easy to accidentally punch through to the deeper subcutaneous layer.
More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.
Aspirin may benefit 11 different cancers, including those of the colon, pancreas, lungs, prostate, breasts, and leukemia.
After 5 years of being diagnosed with rheumatoid arthritis, one every three patients will no longer be able to work.

