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Although the Roman numeral for the number 4 has always been taught to have been "IV," according to historians, the ancient Romans probably used "IIII" most of the time. This is partially backed up by the fact that early grandfather clocks displayed IIII for the number 4 instead of IV. Early clockmakers apparently thought that the IIII balanced out the VIII (used for the number 8) on the clock face and that it just looked better.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.
Cytomegalovirus affects nearly the same amount of newborns every year as Down syndrome.
The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.
For pediatric patients, intravenous fluids are the most commonly cited products involved in medication errors that are reported to the USP.