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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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Urine turns bright yellow if larger than normal amounts of certain substances are consumed; one of these substances is asparagus.
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In 1864, the first barbiturate (barbituric acid) was synthesized.