Answer to Question 1
1. Prosthetic heart valves
2. Aspirin use
3. Ibuprofen use
Rationale:
Prosthetic heart valves and medications such as aspirin and ibuprofen are associated with hemolytic anemia. Acetaminophen use is not associated with hemolytic anemia. Hemolytic anemia is not associated with diet.
Answer to Question 2
4. Loss of the kidney hormone erythropoietin
Rationale:
The anemia associated with renal failure is related to the loss of erythropoietin, which is produced by the healthy kidney and stimulates bone marrow to produce red blood cells. The anemia is not directly related to anorexia or hemodialysis, although these factors may be somewhat associated with the anemia. Renal failure causes the loss of protein, not blood, through the urine.