Answer to Question 1
ANS: 2
Clients with congestive heart failure have impaired circulation, which impairs medication delivery to the intended site of action. Therefore the efficacy of medications in these clients is delayed or altered. The other options reflect possible barriers, but they are not as directly responsible as is the heart's functional capacity
Answer to Question 2
ANS: 4
Each route of medication administration has a different rate of absorption. When applying medi-cations on the skin, absorption is slow because of the physical makeup of the skin. Medications placed on the mucous membranes and respiratory airways are quickly absorbed because these tissues contain many blood vessels. Because orally administered medications pass through the gastrointestinal tract, the overall rate of absorption is usually slow. Intravenous (IV) injection produces the most rapid absorption because medications are immediately available when they enter the systemic circulation.