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The FDA recognizes 118 routes of administration.
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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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Most women experience menopause in their 50s. However, in 1994, an Italian woman gave birth to a baby boy when she was 61 years old.
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The Romans did not use numerals to indicate fractions but instead used words to indicate parts of a whole.
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The first documented use of surgical anesthesia in the United States was in Connecticut in 1844.