The mechanism of action of colony-stimulating factors, such as ...

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The mechanism of action of colony-stimulating factors, such as filgrastim (Neupogen), is to
 
  1. increase neutrophil production.
  2. supplement iron in the body.
  3. replace vitamin B12 factor.
  4. increase erythrocyte production.

Question 2

Per classification of anemias, the morphology for pernicious anemia or folate-deficiency anemia results in
 
  1. hematocytichematoch romic erythrocytes.
  2. microcytichypochrom ic erythrocytes.
  3. macrocyticnormochro mic erythrocytes.
  4. normocyticnormochro mic erythrocytes.

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Answer to Question 1

Correct Answer: 1
Rationale 1: The primary mechanism of action is to increase neutrophil production and phagocytosis in chemotherapy clients.
Rationale 2: Anti-anemic iron supplements increase iron in the body.
Rationale 3: Anti-anemic vitamin supplements increase B12 in the body.
Rationale 4: Hematopoietic growth factors increase erythrocytes in the bone marrow.

Answer to Question 2

Correct Answer: 3
Rationale 1: Hematocytichematoch romic erythrocytes do not classify anemias.
Rationale 2: Microcytichypochrom ic erythrocytes classify iron-deficiency anemia or thalassemia.
Rationale 3: Macrocyticnormochro mic erythrocytes classify pernicious and folate-deficiency anemia.
Rationale 4: Normocyticnormochro mic erythrocytes classify aplastic, hemorrhagic, sickle-cell, and hemolytic anemia.

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