The nurse is reviewing the medication administration record for a ...

[fagboi]

The nurse is reviewing the medication administration record for a group of patients and recognizes that which agents have nonspecific cellular responses?
 
  1. Ethyl alcohol
  2. General anesthetics
  3. Osmotic diuretics
  4. Calcium channel blockers
  5. Alpha-adrenergic antihypertensives

Question 2

The nurse is preparing to administer a medication to a patient on a medical-surgical unit. The median lethal dose of the drug is 40 mg, and the median effective dose is 10 mg. The nurse calculates the therapeutic index to be _____.
 
  What will be an ideal response?

[dlook33]

Answer to Question 1

Correct Answer: 1,2,3
Rationale 1: Ethyl alcohol is an example of an agent that acts by nonspecific mechanisms, independently of cellular receptors.
Rationale 2: General anesthetics are an example of agents that act by nonspecific mechanisms, independently of cellular receptors.
Rationale 3: Osmotic diuretics are an example of agents that act by nonspecific mechanisms, independently of cellular receptors.
Rationale 4: Calcium channel blockers have a specific mechanism of action.
Rationale 5: Alpha-adrenergic antihypertensives have a specific mechanism of action.

Answer to Question 2

Correct Answer: 4
Rationale : The therapeutic index is calculated by dividing the median lethal dose (LD50) by the median effective dose (ED50).

[fagboi]

Both answers were spot on, thank you once again

[dlook33]

Great! Please up vote