Author Question: Which of the following effects would be considered a therapeutic effect of a bisphosphonate drug ... (Read 47 times)

Lisaclaire · **on:** Jul 23, 2018

Which of the following effects would be considered a therapeutic effect of a bisphosphonate drug such as etidronate (Didronel)?

a. Alteration in the level of phosphorus in the bloodstream
b. Reduction of the absorption of vitamin D in the gastrointestinal (GI) tract
c. Inhibition of the absorption of calcium in the GI tract
d. Prevention of bone resorption by inhibiting osteoclasts

Question 2

A home care patient taking levothyroxine (Synthroid) measures the pulse, finds it to be 110 beats per minute, and notifies his health care provider. Which action would be the most appropriate response of the health care provider?

a. Withhold the dose, and notify the prescriber of the drug.
b. Skip the daily dose, and resume the following day.
c. Take the drug every other day for 1 week.
d. Discontinue the drug altogether.

kingdude89 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: D
Bisphosphonates bind to bone crystals to specifically inhibit the activity of osteoclasts, which in turn reduces bone resorption without affecting bone formation. However, since bone formation and resorption come together in the bone turnover process, bone formation does ultimately de-crease.

Answer to Question 2

ANS: A
A resting pulse rate over 100 beats per minute may indicate overdose. The drug should be with-held, and the prescribing health care provider should be notified.