Author Question: A patient is receiving aldesleukin, or interleukin-2 (IL-2), as an immunosuppressant. Which of the ... (Read 54 times)

jessicacav · **on:** Jul 23, 2018

A patient is receiving aldesleukin, or interleukin-2 (IL-2), as an immunosuppressant. Which of the following complications may develop during the first 12 hours after the start of the infusion?

a. Capillary leak syndrome
b. Bradycardia
c. Respiratory depression
d. Low core temperature

Question 2

The patient is a 5-year-old child who is receiving a dosage of diphtheria-pertussis-tetanus (DPT) vaccine. What is the expected duration of the vaccine in a child of this age?

a. 1 year
b. 3 years
c. 5 years
d. 10 years

kswal303 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: A
Capillary leak syndrome is a serious complication of IL-2. Plasma proteins and fluid leak into ex-travascular spaces, resulting in a loss of vascular tone, which in turn reduces blood pressure and, 2 to 12 hours after administration, a decrease in perfusion to body organs. Patients with signifi-cant cardiac, pulmonary, renal, hepatic, or central nervous system (CNS) impairment related to use of IL-2 require very close monitoring.

Answer to Question 2

ANS: D
The duration for the vaccine when administered to a child 2 months to 7 years of age is 10 years.