Author Question: Which body system is primarily responsible for drug elimination? a. Respiratory b. ... (Read 59 times)

shenderson6 · **on:** Jul 23, 2018

Which body system is primarily responsible for drug elimination?

a. Respiratory
b. Gastrointestinal (GI)
c. Renal
d. Hepatic

Question 2

Review the following reactions and select the one that is considered to be part of phase II of the drug biotransformation process.

a. Oxidation
b. Conjugation
c. Alkylation
d. Acetylation

sultana.d · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: C
The kidneys are the primary organ system responsible for drug elimination. To a lesser extent, the GI tract, the respiratory system, sweat, saliva, tears, and breast milk are also involved.

Answer to Question 2

ANS: B
Conjugation, a phase II reaction, forms a covalent bond between the functional group added by the phase I reaction (or, occasionally, some other functional group) and a highly polar molecule derived from within the body.