A nurse should recognize that administering antacids to clients ...

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A nurse should recognize that administering antacids to clients taking which of the following medications can result in decreased drug absorption and decreased drug effects? Select all that apply.
 
  A) Simvastatin (Zocor)
  B) Isoniazid (Nydrazid)
  C) Digoxin (Lanoxin)
  D) Phenytoin (Dilantin)
  E) Enalapril (Vasotec)

Question 2

A client is diagnosed with an infection with H. pylori. Which of the following drugs are commonly used in combination with certain antibiotics in the treatment of this infection? Select all that apply.
 
  A) Metoclopramide (Reglan)
  B) Omeprazole (Prilosec)
  C) Ondansetron (Zofran)
  D) Lansoprazole (Prevacid)
  E) Promethazine (Phenergan)

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Answer to Question 1

Ans: B, C, D
Feedback:
Antacids decrease the absorption of digoxin, isoniazid, phenytoin, and chlorpromazine, leading to decreased effect of those drugs.

Answer to Question 2

Ans: B, D
Feedback:
The proton pump inhibitors, like omeprazole (Prilosec) and lansoprazole (Prevacid), are commonly used in combination with certain antibiotics in the treatment of H. pylori.

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