A nurse is administering an IV infusion of amphotericin B. The ...

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A nurse is administering an IV infusion of amphotericin B. The nurse would be alert for which of the following adverse reactions during the first 30 to 60 minutes of the infusion? Select all that apply.
 
  A) Muscle pain
  B) Hypotension
  C) Nausea
  D) Decreased renal function
  E) Chills

Question 2

After teaching a group of nursing students about amphotericin B, the instructor determines that the teaching was successful when the students identify which of the following as true? Select all that apply.
 
  A) The drug is light sensitive.
  B) It can be administered via IM injection.
  C) The drug can cause renal damage.
  D) Amphotericin B is administered in the outpatient setting.
  E) The drug should be used within 8 hours.

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Answer to Question 1

Ans: B, C, E
Feedback:
When the nurse administers amphotericin B by IV infusion, immediate adverse reactions can occur within 15 to 20 minutes of beginning the infusion, including nausea, vomiting, hypotension, tachypnea, fever, and chills; therefore, it is important for the nurse to carefully monitor the client's temperature, pulse, respirations, and blood pressure during the first 30 to 60 minutes of treatment.

Answer to Question 2

Ans: A, C, E
Feedback:
Amphotericin B is given only under close supervision in the hospital setting, can cause renal damage, is given IV usually over a period of 6 hours, and should be protected from light and used within 8 hours of reconstitution.

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