A nurse is to administer sulfasalazine to a client with ...

[nramada]

A nurse is to administer sulfasalazine to a client with ulcerative colitis. Which of the following interventions would be most important while caring for this client?
 
  A) Stop dosage if skin turns orange-yellow color.
  B) Regularly inspect client's stool samples.
  C) Give the drug on an empty stomach.
  D) Administer cranberry juice to the client.

Question 2

A client is prescribed sulfadiazine one tablet twice daily for 10 days. When reviewing the client's history, the nurse notes that the client is also taking warfarin. The nurse would be alert for which of the following?
 
  A) Prolonged clotting times
  B) Increased risk of infection
  C) Decreased antibiotic effect
  D) Decreased white blood cell count

[cassie_ragen]

Answer to Question 1

Ans: B
Feedback:
While providing care to a client receiving sulfasalazine therapy for ulcerative colitis, the nurse should regularly inspect all stool samples and record their number and appearance. Yellow skin or urine in clients receiving sulfasalazine is normal, and the nurse should not stop the dosage. Sulfasalazine is administered with meals or immediately afterward, not on an empty stomach. Administering cranberry juice is helpful for clients with urinary tract infections, but not for clients with ulcerative colitis.

Answer to Question 2

Ans: A
Feedback:
When warfarin and sulfonamides are given concomitantly, an increase in action of the anticoagulant is seen, leading to an increase in clotting time, such as PT/INR, and an increased risk of bleeding. An increased risk of infection and a decrease in the white blood cell count would occur when a sulfonamide is given with methotrexate. The combination of warfarin and sulfonamide does not impact the effect of the antibiotic.

[nramada]

TYSM

[amandalm]

Excellent