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Author Question: In aging patients, distribution of drugs may be lessened because of a decline in total body water ... (Read 92 times)

pane00

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on: Jul 23, 2018
In aging patients, distribution of drugs may be lessened because of a decline in total body water and lean body mass, warranting the use of decreased dosing. Which drugs are distributed into body water or lean muscle mass and may lead to increased effects
 
  effects and possible toxicity for the aging patient? (Select all that apply.)
  a.
  Digoxin (Lanoxin)
  b.
  Gentamicin (Garamycin)
  c.
  Meperidine (Demerol)
  d.
  Acetaminophen (Tylenol)
  e.
  Ibuprofen (Motrin)

Question 2

The nurse is evaluating the patient's understanding of how to decrease the risk of developing heart disease. Which would be the correct response made by the patient to the nurse?
 
  a. I will take a daily dose of folic acid and vitamins B6 and B12.
  b. I will take folic acid every other day.
  c. I will take calcium supplements daily with meals.
  d. There are currently no vitamins or minerals available to decrease my risk of developing heart disease.


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leahm14

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Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: A, B, C
Drugs that are distributed into body water or lean body mass include digoxin, cimetidine, lithium, gentamicin, meperidine, phenytoin, and theophylline.

Answer to Question 2

ANS: A
Folic acid and vitamins B6 and B12 have been shown to reduce homocysteine levels. Modestly elevated homocysteine levels in the blood are a risk factor for heart disease.


pane00

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Reply #2 on: Jul 23, 2018
Both answers were spot on, thank you once again


leahm14

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Reply #3 on: Jul 23, 2018
Great! Please up vote :D


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