Answer to Question 1
2
Rationale 1:Thyroid agents would be used for hypothyroid conditions.
Rationale 2:Antithyroid agents would be used for hyperthyroid conditions.
Rationale 3:Corticosteroids are used for Addison disease.
Rationale 4:Hormone replacement is not used for hyperthyroidism.
Global Rationale: Hyperthyroidism is the over secretion of the either TSH or thyroid hormone. Antithyroid agents, surgery, or ionizing radiation to kill or inactivate some of the hyperactive thyroid cells.
Answer to Question 2
2
Rationale 1: Addison disease is the hyposecretion of corticosteroids.
Rationale 2: Adverse effects of levothyroxine (Levothroid) resemble symptoms of hyperthyroidism. These include anxiety, insomnia, and weight loss.
Rationale 3: Hyperparathyroidism is hypersecretion of the parathyroid hormone and not use of levothyroxine.
Rationale 4:Anxiety is one adverse effect associated with levothyroxine.
Global Rationale: The difference between a therapeutic dose of levothyroxine and one that produces adverse effects is quite narrow. Adverse effects of levothyroxine resemble symptoms of hyperthyroidism and include tachycardia, anxiety, tremors, insomnia, weight loss, and heat intolerance. Menstrual irregularities may occur in women. A laboratory test is necessary, and the dose may need to be lowered.