Author Question: A client is undergoing antineoplastic therapy. The nurse, in an effort to minimize the toxic effects ... (Read 137 times)

shofmannx20 · **on:** Jul 23, 2018

A client is undergoing antineoplastic therapy. The nurse, in an effort to minimize the toxic effects of therapy, administers which growth factor?

1. Filgrastim (Neupogen)
2. Megestrol (Megace)
3. Carmustine (Gliadel)
4. Teniposide (Vumon)

Question 2

The nurse is caring for a client who is diagnosed with Kaposi sarcoma. Which medication does the nurse anticipate to be included in the plan of care?

1. Letrozole (Femara)
2. Doxorubicin (Adriamycin)
3. Interferon alfa-2 (Roferon A)
4. Paclitaxel (Taxol)

ashely1112 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

1

Rationale 1: Filgrastim (Neupogen) is an immunotherapy, technically a biological response modifier, and is given to minimize the toxic effects of other antineoplastics.
Rationale 2: Megestrol (Megace) is a hormone blocker used for uterine and renal cancer.
Rationale 3: Carmustine (Gliadel) is an alkylating agent used for Hodgkin disease, malignant melanoma, multiple myeloma, and brain tumors.
Rationale 4: Teniposide (Vumon) is a plant extract used for acute lymphocytic leukemia.

Global Rationale: Filgrastim (Neupogen) is an immunotherapy, technically a biological response modifier, and is given to minimize the toxic effects of other antineoplastics. Megestrol (Megace) is incorrect because it is a hormone blocker used for uterine and renal cancer. Carmustine (Gliadel) is incorrect because it is an alkylating agent used for Hodgkin disease, malignant melanoma, multiple myeloma, and brain tumors. Teniposide (Vumon) is incorrect because it is a plant extract used for acute lymphocytic leukemia.

Answer to Question 2

3

Rationale 1: Letrozole (Femara) is a hormone blocker used to treat advanced breast cancer.
Rationale 2: Doxorubicin (Adriamycin) is an antitumor antibiotic used to treat lymphomas, sarcomas, acute leukemia, and cancers of the breast, lung, testes, thyroid, and ovary.
Rationale 3: Interferon alfa-2 (Roferon A) is a biologic response modifier used to treat hairy cell leukemia and Kaposi sarcoma.
Rationale 4: Paclitaxel (Taxol) is a plant extract used to treat ovarian and breast cancers.

Global Rationale: Interferon alfa-2 (Roferon A) is a biologic response modifier used to treat hairy cell leukemia and Kaposi sarcoma.