Answer to Question 1
1, 2, 3, 5
Rationale 1: Use with anticoagulants will increase the risk of bleeding.
Rationale 2: Use of protein pump inhibitors will increase the risk of bleeding.
Rationale 3:Thrombolytic agentswill increase the risk of bleeding.
Rationale 4:Some antibiotics can diminish the antiplatelet actions of clopidogrel.
Rationale 5: Aspirin is an antiplatelet and can cause an increased risk of bleeding.
Global Rationale: Use with anticoagulants, other antiplatelet agents, thrombolytic agents, or NSAIDs, including aspirin and ibuprofen, will increase the risk of bleeding. Protein pump inhibitors, rifampin, or carbamazepine may increase the anticoagulant activity of clopidogrel.
Answer to Question 2
1
Rationale 1: The anticoagulant effect of a single dose of aspirin can last for as long as a week.
Rationale 2:The anticoagulant effect of a single dose of aspirin can last for as long as a week.
Rationale 3:The anticoagulant effect of a single dose of aspirin can last for as long as a week.
Rationale 4:The anticoagulant effect of a single dose of aspirin can last for as long as a week.
Global Rationale: The anticoagulant effect of a single dose of aspirin can last for as long as a week.