Answer to Question 1
2
Rationale 1: Drowsiness and lethargy are not associated with procainamide.
Rationale 2: The most common side effects of procainamide therapy are gastrointestinal, and include nausea, vomiting, and diarrhea.
Rationale 3: Anxiety and tremors are not associated with procainamide.
Rationale 4:Confusion and dizziness are not associated with procainamide.
Global Rationale: The most common side effects of procainamide therapy are gastrointestinal, and include nausea, vomiting, diarrhea, and headache.
Answer to Question 2
4
Rationale 1:Digoxin (Lanoxin) is incorrect because amiodarone can last 48 weeks after the drug is discontinued because it has an extended half-life that can exceed 100 days.
Rationale 2:Verapamil (Calan) is incorrect because amiodarone can last 48 weeks after the drug is discontinued because it has an extended half-life that can exceed 100 days.
Rationale 3:Propranolol (Inderal) is incorrect because amiodarone can last 48 weeks after the drug is discontinued because it has an extended half-life that can exceed 100 days.
Rationale 4: Amiodarone is available as oral tablets and as an IV infusion. IV infusions are limited to short-term therapy, normally only 24 days. Its onset of action can take several weeks when the drug is given orally. Its effects, however, can last 48 weeks after the drug is discontinued because it has an extended half-life that can exceed 50 days.
Global Rationale: Amiodarone is available as oral tablets and as an IV infusion. IV infusions are limited to short-term therapy, normally only 24 days. Its onset of action can take several weeks when the drug is given orally. Its effects, however, can last 48 weeks after the drug is discontinued because it has an extended half-life that can exceed 100 days.
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