Author Question: A patient has been changed from a first generation H1 receptor antagonist to a second generation H1 ... (Read 59 times)

rmenurse · **on:** Jul 23, 2018

A patient has been changed from a first generation H1 receptor antagonist to a second generation H1 receptor antagonist. The nurse evaluates that the patient understands the benefit of this change when which statement is made?

1. I can drink a few beers over the weekend and still take this drug.
2. This drug will not dry out my mouth.
3. This drug will not affect my ability to urinate.
4. This drug will not make me as sleepy.

Question 2

A nurse educator is teaching pharmacokinetics to the pharmacology class. What statement, made by a student, would show the class understands this term?

1. Pharmacokinetics describes how the body absorbs, distributes, metabolizes, and excretes drugs.
2. Pharmacokinetics is how drugs activate specific receptors.
3. Pharmacokinetics is what a drug does to the body.
4. Pharmacokinetics is the efficacy of a drug.

angrybirds13579 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

4
Rationale 1: Alcohol use is still discouraged because of the additive sedation effects.
Rationale 2: This drug will still have some anticholinergic effects.
Rationale 3: This drug will still have some anticholinergic effects.
Rationale 4: Second generation H1 receptor antagonists have less of a sedative effect than do first generation drugs.
Global Rationale: Second generation H1 receptor antagonists have less of a sedative effect than do first generation drugs. Alcohol use is still discouraged because of the additive sedation effects. This drug will still have some anticholinergic effects.

Answer to Question 2

1

Rationale 1: Pharmacokinetics describes how the body absorbs, distributes, metabolizes, and excretes drugs.
Rationale 2:Drugreceptor interactions describe, in part, what effects a drug has on the body, and thus are considered part of pharmacodynamics.
Rationale 3:Pharmacodynamics is the term that describes what effects a drug has on the body.
Rationale 4:Efficacy is a pharmacodynamic concept.

Global Rationale: Pharmacokinetics describes how the body absorbs, distributes, metabolizes, and excretes drugs. Pharmacokinetics is how drugs activate specific receptors is incorrect because drugreceptor interactions describe, in part, what effects a drug has on the body, and thus are considered part of pharmacodynamics. Pharmacokinetics is what a drug does to the body is incorrect because pharmacodynamics is the term that describes what effects a drug has on the body. Pharmacokinetics is the efficacy of a drug is incorrect because efficacy is a pharmacodynamic concept.