Author Question: From a pharmacology standpoint, which statement best explains why levodopa is superior to dopamine? ... (Read 34 times)

james9437 · **on:** Jul 23, 2018

From a pharmacology standpoint, which statement best explains why levodopa is superior to dopamine?

1. It crosses the bloodbrain barrier.
2. It has fewer adverse effects.
3. It has less risk for addiction.
4. It can be administered orally.

Question 2

The nurse conducts group education for clients with seasonal allergies and teaches about the role of histamine. The nurse evaluates that the education has been effective when the clients make which statement?

1. Histamine is inhibited by nonsteroidal anti-inflammatory drugs (NSAIDs).
2. Histamine dilates the vessels in the nose, so it is congested and stuffy.
3. Histamine constricts vessels, causing capillaries to become more permeable.
4. Histamine is primarily stored in phagocyte cells in the skin.

fur · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

1
Rationale 1: Levodopa can cross the bloodbrain barrier, but dopamine cannot. Levodopa administration leads directly to dopamine synthesis.
Rationale 2: Levodopa does not have fewer side effects.
Rationale 3: There is no risk for addiction from either substance.
Rationale 4: Route of administration is not a factor.
Global Rationale: Levodopa can cross the bloodbrain barrier, but dopamine cannot. Levodopa administration leads directly to dopamine synthesis. Levodopa does not have fewer side effects. There is no risk for addiction from either substance. Route of administration is not a factor.

Answer to Question 2

2
Rationale 1: Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit the synthesis of prostaglandins and do not affect histamine.
Rationale 2: Histamine dilates blood vessels causing capillaries to become more permeable. The affected area may become congested with blood.
Rationale 3: Histamine dilates, not constricts, vessels, causing capillaries to become more permeable.
Rationale 4: Histamine is primarily stored in mast cells, not phagocyte cells.
Global Rationale: Histamine dilates blood vessels causing capillaries to become more permeable. The affected area may become congested with blood. Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit the synthesis of prostaglandins and do not affect histamine. Histamine dilates, not constricts, vessels, causing capillaries to become more permeable. Histamine is primarily stored in mast cells, not phagocyte cells.