Author Question: Which sign or symptom associated with the adverse effects of nelfinavir (Viracept) would most ... (Read 37 times)

jlmhmf · **on:** Jul 23, 2018

Which sign or symptom associated with the adverse effects of nelfinavir (Viracept) would most concern the nurse?

a. Blood glucose level of 78 mg/dL
b. Poor turgor and dry mucous membranes
c. Tingling in the extremities
d. Weight loss of 5 pounds in 2 weeks

Question 2

The nurse is caring for a patient on a protease inhibitor (PI). Upon review of the laboratory test results, the nurse notes that the patient has newly elevated plasma triglycerides and cholesterol.

The nurse expects that the prescriber will manage these levels with:
a. lovastatin (Mevacor).
b. simvastatin (Zocor).
c. modified diet and exercise.
d. pancrease.

Sophiapenny · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: B
A dose-limiting effect of nelfinavir is moderate to severe diarrhea, which can lead to dehydration. It may also cause hyperglycemia; a blood glucose level of 78 mg/dL is not indicative of hyperglycemia. Nelfinavir is not known to cause tingling in the extremities or weight loss.

Answer to Question 2

ANS: C
All PIs can elevate plasma levels of cholesterol and triglycerides. Potential interventions for hyperlipidemia include modified diet, exercise, and lipid-lowering agents. Lovastatin and simvastatin should be avoided, because they can accumulate to dangerous levels. Pancrease is not indicated to lower triglycerides and cholesterol.