Author Question: Which are benefits of using a combination of two or more antibiotics? (Select all that apply.) a. ... (Read 92 times)

waynest · **on:** Jul 23, 2018

Which are benefits of using a combination of two or more antibiotics? (Select all that apply.)

a. Reduced cost
b. Reduced risk of suprainfection
c. Reduced toxicity
d. Reduced resistance
e. Reduced risk in severe infection

Question 2

Which methods have been identified for preventing antimicrobial resistance? (Select all that apply.)

a. Administering influenza vaccine
b. Stopping antibiotic therapy as soon as possible when treating infection
c. Treating bacterial colonization in asymptomatic patients
d. Using narrow-spectrum antibiotics when possible
e. Using national data to determine antimicrobial drug selection

Carliemb17 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: C, D, E
In some situations, an antibiotic combination can reduce toxicity, because the dosage of a more toxic agent can be reduced. Drug combinations can be used to suppress the emergence of resistant bacteria in the treatment of tuberculosis. With a severe infection, a combination of antibiotics is useful until culture results are known to ensure that all possible sources of infection are treated. Using multiple antibiotics is more costly and poses a greater risk of suprainfection.

Answer to Question 2

ANS: A, B, D
Vaccines help prevent disease and thus reduce the need to use antimicrobial drugs. Discontinuing antibiotic therapy as soon as possible, such as when an infection has been fully treated or when an infection is unlikely, helps reduce exposure of normal flora and other microbes to antimicrobials. Narrow-spectrum antibiotics target the pathogen and are less likely to act against other microbes. It is not correct to treat bacterial colonization when patients are asymptomatic. Local data give clearer information on local trends in susceptibility and resistance and thus are more likely to guide antimicrobial drug selection correctly.