A nurse is explaining to a nursing student how clomiphene ...

[crobinson2013]

A nurse is explaining to a nursing student how clomiphene (Clomid) works to improve fertility. Which statement by the student indicates a need for further teaching?
 
  a. Clomiphene blocks estrogen receptors to cause increased secretion of gonadotropins.
  b. Clomiphene directly stimulates the ovary, causing follicular maturation and ovulation.
  c. If follicular maturation is the only result of clomiphene therapy, human chorionic gonadotropin may be given.
  d. If the pituitary gland cannot produce LH and FSH, clomiphene will not be effective.

Question 2

A patient with infertility will begin taking menotropins (Repronex). The nurse will evaluate this patient's history to determine whether the:
 
  a. patient has a history of hyperinsulinemia.
  b. patient has excessive prolactin secretion.
  c. patient's pituitary can produce LH and FSH.
  d. patient's ovaries are capable of responding to gonadotropins.

[carlsona147]

Answer to Question 1

ANS: B
Clomiphene blocks receptors for estrogen; it does not directly stimulate the ovary. When estrogen receptors are blocked, the pituitary increases production of the gonadotropins LH and FSH. Clomiphene may produce follicular maturation without ovulation, and hCG will be given to produce ovulation. Without a pituitary capable of producing LH and FSH, clomiphene will not be effective.

Answer to Question 2

ANS: D
Menotropins are used when gonadotropin secretion by the pituitary is insufficient to provide adequate ovarian stimulation. Candidates must have ovaries capable of responding to FSH and LH. Metformin is used for hyperinsulinemia. Women with excessive prolactin secretion are treated with cabergoline. Menotropin contain equal amounts of LH and FSH and act directly on the ovaries, so the pituitary's inability to produce these hormones is not a factor for beginning treatment with this drug.

[crobinson2013]

Both answers were spot on, thank you once again

[carlsona147]

Great! Please up vote