A patient has developed muscarinic antagonist toxicity from ...

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A patient has developed muscarinic antagonist toxicity from ingestion of an unknown chemical. The nurse should prepare to administer which medication?
 
  a. Atropine (Sal-Tropine) IV
  b. Physostigmine (Antilirium)
  c. An acetylcholinesteras e activator
  d. Pseudoephedrine (Ephedrine)

Question 2

A prescriber has ordered bethanechol (Urecholine) for a postoperative patient who has urinary retention.
 
  The nurse reviews the patient's chart before giving the drug. Which part of the patient's history would be a contraindication to using this drug?
  a. Asthma as a child
  b. Gastroesophageal reflux
  c. Hypertension
  d. Hypothyroidism

[elizabethrperez]

Answer to Question 1

ANS: B
Physostigmine is indicated for muscarinic antagonist toxicity. Atropine is a drying agent and would only complicate the drying action that arises from the muscarinic antagonist. An acetylcholinesteras e activator would only contribute to dryness that arises from the muscarinic antagonist. Ephedrine is not indicated for muscarinic antagonist toxicity.

Answer to Question 2

ANS: A
Bethanechol is contraindicated in patients with active or latent asthma, because activation of muscarinic receptors in the lungs causes bronchoconstriction . It increases the tone and motility of the gastrointestinal (GI) tract and is not contraindicated in patients with reflux. It causes vasodilation and would actually lower blood pressure in a hypertensive patient. It causes dysrhythmias in hyperthyroid patients.

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TYSM

[rachel]

Excellent