Answer to Question 1
Correct Answer: 4
Rationale 1: Sildenafil (Viagra) does not cause an erection.
Rationale 2: Sildenafil (Viagra) does not restrict blood flow to the penis.
Rationale 3: Sildenafil (Viagra) does not stimulate the release of phosphodiesterase-5.
Rationale 4: Sildenafil (Viagra) inhibits the release of phosphodiesterase-5, which relaxes smooth muscle in the corpus cavernosa and allows an increase of blood flow to the penis, causing an erection.
Global Rationale: Sildenafil (Viagra) inhibits the release of phosphodiesterase-5, which relaxes smooth muscle in the corpus cavernosa and allows an increase of blood flow to the penis, causing an erection. The medication itself does not cause an erection. It does not restrict blood flow to the penis and does not stimulate release of phosphodiesterase-5.
Answer to Question 2
Correct Answer: 2
Rationale 1: Having a sexually transmitted disease is not a contraindication to taking tadalafil (Cialis).
Rationale 2: Combining tadalafil (Cialis) with nitroglycerin can lead to serious hypotension.
Rationale 3: Having diabetes mellitus is not a contraindication to taking tadalafil (Cialis).
Rationale 4: Taking blood pressure medication is not a contraindication to the use of tadalafil (Cialis).
Global Rationale: Combining tadalafil (Cialis) with nitroglycerin can lead to serious hypotension. Having a sexually transmitted disease, having DM, and taking blood pressure medication are not contraindications to taking tadalafil (Cialis).