Which statement best explains the mechanism of action of ...

[ts19998]

Which statement best explains the mechanism of action of monoclonal antibodies?
 
  1. They alter the DNA of the tumor cells.
  2. They prevent replication of the tumor cells.
  3. They stimulate immune cell function.
  4. They attack antigens on the surface of specific tumor cells.

Question 2

When administering vincristine, the nurse knows that its dose-limiting toxicity primarily affects what system?
 
  1. Renal
  2. Pulmonary
  3. Cardiac
  4. Central nervous system

[cloudre37]

Answer to Question 1

Correct Answer: 4
Rationale 1: This is not the mechanism of action of monoclonal antibodies.
Rationale 2: This is not the mechanism of action of monoclonal antibodies.
Rationale 3: They are immunosuppressants.
Rationale 4: This is the correct mechanism of action of monoclonal antibodies.
Global Rationale: Monoclonal antibodies are a form of targeted therapy. They bind to antigens on the surface of tumor cells, marking the cell for destruction. They are not immunosuppressants and do not alter the DNA or prevent tumor cells from replicating.

Answer to Question 2

Correct Answer: 4
Rationale 1: Although important, the renal system is not the system primarily affected by vincristine.
Rationale 2: Although important, the pulmonary system is not the system primarily affected by vincristine.
Rationale 3: Although important, the cardiac system is not the system primarily affected by vincristine.
Rationale 4: The system primarily affected by the dose-limiting toxicity of vincristine is the central nervous system.
Global Rationale: The major dose-limiting toxicity of vincristine is neurotoxicity. The other systems may be affected, but not with the major dose-limiting effects.

[ts19998]

Thank you!

[cloudre37]

Always glad to help...