Author Question: A client is receiving a cell-cycle-specific medication for the treatment of leukemia. The nurse ... (Read 201 times)

crazycityslicker · **on:** Jul 23, 2018

A client is receiving a cell-cycle-specific medication for the treatment of leukemia. The nurse recognizes that in order for these drugs to kill the most cancer cells, they should be administered in:

1. divided, infrequent doses.
2. divided, frequent doses.
3. a single dose each day.
4. a large, one-time dose.

Question 2

Which statement most accurately describes the action that occurs during stage S (synthesis) of the cell cycle?

1. The cell undergoes prophase, metaphase, anaphase, and telophase.
2. The cell makes additional proteins that are necessary for cell division.
3. The cell conducts metabolism, impulse conduction, contraction, or secretion.
4. The cell duplicates its DNA.

mcarey591 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 2
Rationale 1: This is not the most effective administration of cell-cycle-specific drugs.
Rationale 2: Cell-cycle-specific drugs kill the most cancer cells when administered in divided, frequent doses.
Rationale 3: This is not the most effective administration of cell-cycle-specific drugs.
Rationale 4: This is not the most effective administration of cell-cycle-specific drugs.
Global Rationale: Cell cycle specific drugs kill the most cancer cells when they are administered in divided but frequent doses. The other dosing schedules are not the most effective.

Answer to Question 2

Correct Answer: 4
Rationale 1: This describes stage M (mitosis).
Rationale 2: This describes stage G2, or the premitotic stage.
Rationale 3: This describes stage G0, or the resting stage.
Rationale 4: This describes stage S (synthesis).
Global Rationale: During the S phase the cell duplicates its DNA. The cell undergoes prophase, metaphase, anaphase, and telophase in the M (mitosis) phase. The cell makes additional proteins that are necessary for cell division in the G2 or premitoitic stage. The cell conducts metabolism, impulse conduction, contraction, or secretion in the G0 stage.