This topic contains a solution. Click here to go to the answer

Author Question: The nurse on an oncology unit is planning care for clients with various types of cancer. The nurse ... (Read 211 times)

genevieve1028

  • Hero Member
  • *****
  • Posts: 601
The nurse on an oncology unit is planning care for clients with various types of cancer. The nurse recognizes that certain cancer cells have a low growth fraction and are less sensitive to chemotherapeutic agents, including:
 
  Standard Text: Select all that apply.
  1. leukemia cells.
  2. lymphoma cells.
  3. breast cancer cells.
  4. lung cancer cells.
  5. bone marrow cells.

Question 2

A client receiving antineoplastic agents in the treatment of lung cancer has been told that treatment options are limited. The nurse explains that lung cancer has a decreased sensitivity to antineoplastic agents because lung cancer cells:
 
  1. have a very erratic cell cycle, and there is little difference between the number of replicating and resting cells.
  2. grow for a long time before detection and are therefore less sensitive to antineoplastic agents.
  3. grow in a high-oxygen environment and are therefore not very sensitive to antineoplastic agents.
  4. have a low growth fraction, so there is little difference between the number of replicating and resting cells.



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

nathang24

  • Sr. Member
  • ****
  • Posts: 314
Answer to Question 1

Correct Answer: 3,4
Rationale 1: Leukemia cells have a high growth fraction and are more sensitive to chemotherapeutic agents than are cells with a low growth fraction.
Rationale 2: Lymphoma cells have a high growth fraction and are more sensitive to chemotherapeutic agents than are cells with a low growth fraction.
Rationale 3: Breast cancer cells have a low growth fraction and are less sensitive to cell cycle specific chemotherapeutic agents.
Rationale 4: Lung cancer cells have a low growth fraction and are less sensitive to cell cycle specific chemotherapeutic agents.
Rationale 5: Bone marrow cells have a high growth fraction and are more sensitive to chemotherapeutic agents than are cells with a low growth fraction.
Global Rationale: Cell cycle specific drugs are most effective in treating hematologic malignancies and other cancers that have a relatively large proportion of cells proliferating at any given point in time. Examples are leukemia, lymphoma, and bone marrow cancers. Lung cancer and breast cancer have low growth fractions and are less sensitive to cell cycle specific chemotherapeutic agents.

Answer to Question 2

Correct Answer: 4
Rationale 1: Lung cancer cells do not have a very erratic cell cycle.
Rationale 2: Lung cancer cells might grow for a long time before detection, but this is not the primary reason they are less susceptible to antineoplastic agents.
Rationale 3: A high-oxygen environment is not the reason that lung cancer cells are less sensitive to antineoplastic agents.
Rationale 4: The growth fraction is the ratio of the number of replicating cells to the number of resting cells. Antineoplastic drugs are much more toxic to tissues and tumors with high growth fractions. Breast and lung cancers have a low growth fraction.
Global Rationale: Solid tumors such as breast and lung cancer generally have a low growth fraction; therefore, they are less sensitive to antineoplastic agents. Lung cancer cells do not have a very erratic cell cycle. Lung cancer cells might grow for a long time before detection, but this is not the primary reason they are less susceptible to antineoplastic agents. A high-oxygen environment is not the reason that lung cancer cells are less sensitive to antineoplastic agents.




genevieve1028

  • Member
  • Posts: 601
Reply 2 on: Jul 23, 2018
Thanks for the timely response, appreciate it


mammy1697

  • Member
  • Posts: 341
Reply 3 on: Yesterday
Great answer, keep it coming :)

 

Did you know?

Approximately 15–25% of recognized pregnancies end in miscarriage. However, many miscarriages often occur before a woman even knows she is pregnant.

Did you know?

Chronic necrotizing aspergillosis has a slowly progressive process that, unlike invasive aspergillosis, does not spread to other organ systems or the blood vessels. It most often affects middle-aged and elderly individuals, spreading to surrounding tissue in the lungs. The disease often does not respond to conventionally successful treatments, and requires individualized therapies in order to keep it from becoming life-threatening.

Did you know?

During pregnancy, a woman is more likely to experience bleeding gums and nosebleeds caused by hormonal changes that increase blood flow to the mouth and nose.

Did you know?

It is difficult to obtain enough calcium without consuming milk or other dairy foods.

Did you know?

Alzheimer's disease affects only about 10% of people older than 65 years of age. Most forms of decreased mental function and dementia are caused by disuse (letting the mind get lazy).

For a complete list of videos, visit our video library